Introduction
SPARK Taiwan 計畫主要是配合生醫產業發展推動,提供欲投入藥物或醫療器材產品開發,或已有研發成果但缺乏商品化概念的團隊全方面的育成與產業化輔導,並於初期提供早期投資經費協助其產品開發計劃的發展。在過去的十年期間,SPARK Taiwan計畫透過與六所區域大學的合作,包含國立臺灣大學、國立成功大學、台北醫學大學、高雄醫學大學、長庚大學與輔仁大學,截至2023年共輔導了52家新創公司的成立、培育了480個以上的生技醫療相關創業團隊。且超過3,000人次以上參與過SPARK Taiwan的相關課程活動。
The SPARK Program is dedicated to helping academic innovation transition into commercialization. SPARK T aiwan, over the past 10 years, has successfully spun off 52 companies, and executing around 480 biomedical innovation projects. Over 3,000 individuals from universities, research institution, medical centers have participated in this program to translate their research outcomes into products, fostering future teams for industry entry.
Translational Research Bootcamp
Here the Stanford SPARK team will lead participants through the SPARK methodology in an interactive workshop to give them the foundation to discover, develop and deliver new treatments for unmet medical needs. The focus will be on working through real-life problems and solutions.
Global SPARK Meeting
Every year the SPARK Global programs from over 20 countries gather to build collaborations and share our successes and challenges. Importantly we take this opportunity to work together to improve the Global SPARK program.
SPARK Taiwan Asia Showcase
We will share featured programs from SPARK Taiwan with you and present partnering opportunities.
Advisor 指導單位

Organizer 主辦單位





2023 SPARK TAIWAN BOOTCAMP AGENDA
Time | July 24 | Time | July 25 | Time | July 26 |
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09:00-09:20 |
Welcome & Program Overview Emcee, Yu-Feng Jane Tseng, PhDProgram Overview: Kevin Grimes, MD, MBA |
09:00-10:10 | Agenda Overview | 09:00-09:30 | Agenda Overview |
09:20-10:30 | Starting with the End in Mind Clinical Need Assessment & Target Product Profile Development Kevin Grimes, MD, MBA 60 min Lecture, 10 min Q&A |
10:10-10:40 | Developing a Treatment- Chronic Ear Drum Perforations Case study in Product Development Peter Santa Maria, PhD 20 min Lecture, 10 min Q&A |
09:30-10:00 | TPP Working Groups Group Leaders - Kevin Grimes, MD; Peter Santa Maria, MD, PhD; Dirk Mendel, PhD |
10:30-11:00 |
Understanding the Problem Chronic Ear Drum PerforationsCase Study in Product Discovery Peter Santa Maria, MD, PhD 20 min Lecture, 10 min Q&A |
10:40-10:50 |
Coffee Break |
10:00-12:00 |
TPP Pitches 10 min presentations, 10 min Q&A |
11:00-11:10 | Coffee Break | 10:50-12:00 | Target Validation /Pharmacology Dirk Mendel, PhD 60 min Lecture, 10 min Q&A |
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11:10-12:20 | Translating a Therapeutic Discovery Dirk Mendel, PhD 60 min Lecture, 10 min Q&A |
12:00-13:00 |
Delivering an Effective Pitch to Potential Investors Lunch & Learn Peter Santa Maria, MD, PhD 30 min Lecture, 10 min Q&Q |
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12:20-13:20 | Developing Your Target Product Profile(TPP) Lunch & Initial Project Discussions |
13:00-14:10 |
Clinical Trial Design Kevin Grimes, MD, MBA 60 min Lecture, 10 min Q&A |
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13:20-15:05 | A Design Thinking Approach to Translational Medicine Peter Santa Maria, MD, Ph.D 30 min Lecture, 1 hr 15 min Workshop |
14:10-15:10 |
TPP Working Groups Group Leaders - Kevin Grime, MD; Peter Santa Maria, PhD; Dirk Mendel, PhD |
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15:05-15:25 | Coffee & Refreshment Break |
15:10-15:30 |
Coffee & Refreshment Break |
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15:25-17:50 | TPP Working Groups Group Leaders - Kevin Grimes, MD; Peter Santa Maria, MD, PhD; Dirk Mendel, PhD |
15:30-17:50 |
TPP Working Groups Group Leaders - Kevin Grimes, MD; Peter Santa Maria, MD, PhD; Dirk Mendel, PhD |
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18:00-20:00 | Reception Dinner |
2023 GLOBAL SPARK MEETING AGENDA
July 26 (Day 1) | |
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13:30-14:00 |
Welcome Introduction & Program Overview : Yufeng Jane Tseng, PhD, Director SPARK TAIWAN Opening Remarks : Deputy Minister Yi-Juang Chern, National Science and Technology Council |
14:00-14:30 |
SPARK GLOBAL:Where Are We & Where Are We Going? : Peter Santa Maria, MD, PhD, SPARK TAIWAN |
14:30-15:00 | SPARK TAIWAN:Ten Years of SPARKing : Yufeng Jane Tseng, PhD, Director SPARK TAIWAN |
15:00-15:30 | Coffee & Refreshment Break |
15:30-17:00 | SPARK GLOBAL Updates : SPARK Program Directors |
17:00-20:00 | Reception Dinner |
July 27 (Day 2) | |
09:00-09:10 | Wednesday Recap & Thursday Agenda : Yufeng Jane Tseng, PhD |
09:10-11:10 | Competitiveness of Taiwan’s Clinical Trial Medical Regulations : Dr. Hen Dern Chen, MD, PhD, Genomics Research Center, Academic Sinica New Drugs Regulatory Strategies and Guidance : Dr. Sherry Ku, Chairman, Good Group Consultation Corporation Important Trends and Challenges in the Adoption of Smart Technology in Clinical Decision-making Regulations : Dr. Chih-Hsiung Chen, Dean & Professor, National Yang Ming Chiao Tung University Round Table Discussion Concluding Remarks |
11:10-12:10 | From the Benchside to Patient Care - Case Study : Peter Santa Maria, MD, PhD |
12:10-13:00 | Lunch |
13:00-14:00 | From the Benchside to Patient Care - Case Study : Dirk Mendel, PhD |
14:00-15:30 | SPARK GLOBAL Updates & Working Together Workshop : Updates by SPARK Program Directors and Working Together Moderated by Peter Santa Maria, MD, PhD |
15:30-16:00 | Coffee & Refreshment Break |
16:00-18:00 | SPARK GLOBAL Updates & Working Together Workshop : Updates by SPARK Program Directors and Working Together Moderated by Peter Santa Maria, MD, PhD |
18:00-20:00 | Night Market Tour (Optional) Location : Raohe Street Night Market (饒河夜市) |
July 28 (Day 3) | |
09:00-09:10 | Thursday Recap & Friday Agenda : Dr. Yufeng Jane Tseng, PhD, Director of SPARK Taiwan Office |
09:10-10:00 | Panel Bioventure & Commercialization in Japan Market Innovation and Advamces in Biotechnology : Implications for the Japanese Market (20min) : Dr. Shin Kawamata, MD, Ph.D., CEO of Cyto-Facto, Director, Research and Development Center for Cell Therapy, Foundation for Biomedical Research and Innovation Market Access and Commercialization Strategies for Biotech Products in Japan (20min) : Dr. Ken-Ichiro Kosai, MD., Ph.D., Kagoshima University Q&A Concluding Remarks : Dr. Yufeng Jane Tseng, PhD, Director of SPARK Taiwan Office |
10:10-11:10 | Panel : Bioventure & Commercialization in Asia Introduction : Dr. Jane Tsai, Vice President, YFY Biotech Management Dr. Berry Murphy, CRO, NOVOTECH Round Table Discussion : Dr. Jane Tsai, Vice President, YFY Biotech Management ; Dr. Berry Murphy, CRO, NOVOTECH Dr. Michel Chu, Ph.D., President, Industrial Technology Investment Corporation. Dr. Ken-Ichiro Kosai, MD, Ph.D., Kagoshima Universit ; Dr. Reshman Ganapathi, Ph.D., Senior Scientific Advisor, NOVOTECH Concluding Remarks : Yufeng Jane Tseng, PhD |
11:10-12:10 | Concluding Remarks : Peter Santa Maria, MD, PhD and Yufeng Jane Tseng, PhD |
2023 SPARK TAIWAN ASIA SHOWCASE AGENDA
Time | July 28 |
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13:00 - 13:10 | Opening Remarks Welcome from SPARK Global,Professor Peter Santa Maria Welcome from SPARK Taiwan, Professor Yufeng Jane Tseng |
13:10 - 13:25 | National Taiwan University, SPARK Taiwan GLUT Targeting Small Molecule Dug Conjugation for Cancer Therapy Speaker: Pi-Huang Liang |
13:25 - 13:40 | Taipei Medical University, SPARK Taiwan Cancer Stem Cell Isolation Platform for Drug Discovery Speaker: Yao-An Shen |
13:40 - 13:55 | Kaohsiung Medical University, SPARK Taiwan Disease-directed Antibody Lock: Improve patients’ life quality by enhancing the safety and efficacy of antibody Speaker: Yun-Chi Lu, CEO & Co-founder |
13:55 - 14:10 | University of Colorado, SPARK Colorado Rock Immune CCR4-IL2 Bispecific Immunotoxin for Targeted T herapy of Cutaneous T-Cell Lymphoma and Other Cancers Speaker: Zhirui Wang, DVM |
14:10 - 14:25 | National Taiwan University, SPARK Taiwan Novel Therapeutic Agents for Abdominal Pain in Irritable Bowel Syndrome Speaker: Ling-Wei Hsin |
14:25 - 14:40 | FuJen University, SPARK Taiwan CytoSCM: Living Single Cells Microfluidic Capture Microdissection Speaker: Rex Wu, Founder CEO & CTO |
14:40 – 15:10 | Refreshment Break & Coffee |
15:10 - 15:25 | Kaohsiung Medical University, SPARK Taiwan 3D Printable Bone Graft Substitute Speaker: Lily-Lin, CIO / Promotions |
15:25 - 15:40 | University of Colorado, SPARK Colorado The “Button Huggie” A Securement Device for Gastrostomy and Cecostomy Buttons Speaker : Steve Moulton |
15:40 - 15:55 | National Cheng Kung University, SPARK Taiwan aiFREE Intelligent Health Partner Speaker: Y. C. Lin |
15:55 - 16:10 | National Taipei Medical University, SPARK Taiwan Preclinical AI drug discovery and development platform Speaker: Sung Ting Yi |
16:10 - 16:25 | Osaka University, SPARK Japan Development of Electrophysiological Determination of Uterine Receptivity (EDUR) Speaker: Hitomi Nakamura |
16:25 - 17:30 | Networking |
17:30 - 17:40 | Concluding Remarks |
18:00 - 20:00 | Reception Dinner (Invitation Only) |
Speakers
Prof. Daria Mochly-Rosen
Founder and Director of SPARK At Stanford,
Professor of Chemical and Systems Biology, Stanford University School of Medicine
Professor Daria Mochly-Rosen helps academics navigate the so-called “valley of death” between drug discovery and development. Professor Mochly-Rosen founded The SPARK Program at Stanford in 2006 after having to leave academia to start a pharmaceutical company to translate her protein kinase C research into cardiovascular therapeutics. Challenging the academic dogma of how scientific discoveries should reach the pharmaceutical industry, the SPARK model has been implemented internationally and has resulted in a book about drug development from academia. Professor of Chemical and Systems Biology at Stanford, she leads a multi-disciplinary research lab that includes chemists, biochemists, biologists and physician scientists. She has published over 285 papers and over 36 patents and patent applications. Professor Mochly-Rosen is originally from Israel, where she received her doctorate in Chemical Immunology from The Weizmann Institute of Science.
Dr. Michael Ackermann
Director of Biotechnology for the Stanford
University Byers Center for Biodesign,.
Co-founder and Chairman of Tarsus Pharmaceuticals
Michael is Director of Biotechnology for the Stanford University Byers Center for Biodesign. He is also co-founder and serves as Chairman of the Board of Tarsus Pharmaceuticals (NASDAQ: TARS). Michael is also co-founder, former CEO, and serves on the board of Presidio Medical. Previously, he was co-founder and served as Chairman of Oyster Point Pharma, Inc. (NASDAQ: OYST). Prior to this, he was Vice President, Neurostimulation for Allergan (an AbbVie company), after serving as co-founder and CEO of Oculeve, Inc., which was acquired by Allergan, plc. Michael received a BE degree from Vanderbilt University and MS and PhD degrees from Case Western Reserve University. He is a graduate of the Stanford University Biodesign Fellowship and Vision Research Fellowship. He has more than 50 issued US patents and numerous patent applications and peer-reviewed publications.
Prof. Kevin Grimes
Co-Director of SPARK At Stanford
Professor of Chemical and Systems Biology,
Stanford University School of Medicine
Kevin Grimes, MD is Professor of Chemical and Systems Biology and Co-director of the SPARK Program at Stanford. While a Clinical Assistant Professor of Medicine at Stanford, he obtained an MBA at the Stanford Graduate School of Business. He was selected as a White House Fellow and served as Special Assistant to the Secretary of Defense. After 15 years in the biotech industry, he returned to Stanford. SPARK’s mission is to advance promising discoveries to patient care; to educate faculty and trainees regarding the translational process; and to identify more efficient approaches to bring new therapies to patients. The SPARK methodology has been adopted by over 50 academic institutions world-wide. Grimes teaches graduate student courses on drug discovery and development and continues to teach and practice internal medicine. He received the David Rytand Award for Excellence in Clinical Teaching and the Faculty Award for Excellence in Graduate Teaching.
Dr. Jeewon Kim
Program manager of SPARK At Stanford
Jeewon Kim received her undergraduate degree at Seoul National University in Korea and worked at Daesang Ltd, a Food and Drug company in Korea. She did her doctoral work at UC Berkeley in the lab of Dr. Marc Hellerstein, where she developed a stable isotope biomarker to detect early phases of colon cancer. She subsequently worked as a consultant for startup company Kinemed Inc. Then as a postdoctoral fellow, she began drug development work in Dr. Daria Mochly-Rosen’s lab at Stanford, studying the roles of different protein kinase C (PKC) isozymes in breast and prostate cancer. While in Dr. Mochly-Rosen’s lab, she worked to develop small peptides as anticancer drugs. This work has resulted in multiple publications and review papers and identified the roles of PKCs in cancer proliferation, angiogenesis, migration and metastasis. She then worked at the Stanford Cancer Institute Transgenic, Knockout and Tumor model Center (TKTC) as a group lead and preclinical oncology facility manager. She is currently a program manager and associate director of business development at SPARK since 2019.
SPARK Taiwan 計畫辦公室
洪萱芳 專案經理 | 02-2737-7173 | sparktw@narlabs.org.tw
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